Shiseido Power Infusing Concentrate Review

A beloved serum now enhanced with ImuGeneration Technology, featuring botanical extracts of reishi mushroom and iris root.

The Ultimune serum strengthens skin against daily damage and visible signs of aging for skin that’s 28% stronger in just 1 week. It has a silicone base that creates a protective barrier on the skin. That helps a little with protecting skin against daily damage, but it’s not as impressive as Shiseido makes it out to be.

The new formula features an improved dewy texture that sinks quickly into skin, for a longer-lasting, silky smooth fresh feeling.


  • New Ultimune is now enhanced with ImuGeneration Technology™ featuring botanical extracts of Reishi Mushroom and Iris Root, to continuously fortify skin’s ability to defend itself.
  • Powered by Reishi Mushrooms, rich anti-oxidants containing polysaccharides (sugars), known to hydrate and visibly reduce aging. Iris root is recognized for its vitality and ability to keep skin moisturized. Together these ingredients are naturally powerful age defenders for strong, healthy-looking skin.
  • Also features exclusive Ultimune Complex™—Bulgarian rose water, aqua in pool, and yeast extract—protect and strengthen skin against day to day damage and signs of aging, while a powerful botanical blend of gingko biloba leaf extract, shiso, and thyme maintain a healthy-looking skin surface.
  • Features the comforting scent of ImuCalm Compound™ that contains fragrance ingredients of rose and lotus elements and a green floral fragrance.

The Ultimune Power Infusing Concentrate now comes with potent natural extracts specially picked to improve the skin’s ability to defend its own ideal condition.

What that means is that the serum will work to strengthen your skin from within — we’re talking reducing skin inflammation along with promoting cell regeneration and skin healing. Botanical ingredients in its formula include Reishi and Iris extract, gingko, thyme and lotus germ.

A first telltale sign that a product is a no-no for my eczema-ridden skin is when it stings upon application, and I’m happy to note that the serum doesn’t leave my skin with any sort of tingly sensations.

Four weeks later and I can glean some gradual (positive!) differences to my skin. I have yet to experience another bout of eczema around my cheek area, which is a sensitive zone and usually is the first to react to external stressors. No dry patches and red rashes in sight, and my skin texture looks smoother and more refined. I usually refrain from applying excessive foundation, highlighter or blusher around my cheeks for fear of another flare up, but a string of back-to-back work events dictate that I must look my best no matter the cost — and I’m relieved to see that my skin is holding up wonderfully despite layering on makeup on a daily basis.

How to use:

Use every morning and evening after cleansing and before moisturizing. When using with other serums, apply Ultimune Power Infusing Concentrate first. Push the pump twice to dispense formula onto palm of hand and smooth evenly over the face.

If you’re looking for a serum that can power up your skin’s resilience from within, along with giving you an understated glow, you definitely won’t go wrong with the new Shiseido Ultimune Power Infusing Concentrate.

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